Dr. Jolijn R. van Leeuwen

MD, PhD

Lead for the research theme on Digital Health & Real-world Evidence (RWE)

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Publications (ORCID)

Research

I am a physician-scientist and postdoctoral researcher within the LuVaCs team. Focusing on innovating treatment and digital health, I lead the research theme on Digital Health & Real-world Evidence (RWE) and am also closely involved in our clinical trials.

My experiences as a physician, researcher and innovator showed me digital solutions are necessary to make healthcare more efficient and to personalize care for complex high-burden diseases such as ANCA-associated vasculitis (AAV) and SLE. My current work centers on implementing and evaluating digital health solutions to further individualize disease monitoring and treatment for LuVaCs patients. Over recent years, I have led the implementation of smart, hybrid care pathways for patients with AAV and SLE, and am currently analyzing their impact on healthcare utilization. Using artificial intelligence, I am working on further personalizing treatment and monitoring strategies to improve care and quality of life for these patients.

Additionally, I serve as coordinator and sub-principal investigator of the ongoing multicenter ENDURRANCE trial, investigating the combination of rituximab and cyclophosphamide in AAV, and sub-principal investigator of the AVAC-EUR trial, investigating avacopan-based treatment strategies in AAV.

Alongside this research, I contribute to the LuVaCs team by managing data collection, analysis, and dashboarding for our clinical cohorts, offering statistical support, and bridging experimental results with clinical data to ensure meaningful interpretation.


Curriculum vitae

I studied medicine at the University of Amsterdam and obtained my medical degree in 2020. Subsequently, I worked as a clinical resident across the departments of internal medicine, nephrology, gastroenterology, pulmonology, and cardiology at the Zaans Medical Center for one year.

In 2021 I started my PhD at the Leiden University Medical Center supervised by Prof. Dr. Teng. I focused on developing new treatment strategies for ANCA‑associated vasculitis. In particular, I used real‑world patient data to generate clinically meaningful insights aimed at improving and personalizing care. In 2025 I successfully defended my thesis on “Treatment innovation of ANCA-associated vasculitis – unleashing real-world data” and started working as a postdoctoral research within the same team.

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